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Gonal-F

Generic name: follicle stimulating hormoneFOL-ik-al-STIM-ue-lay-ting-HOR-mone ]
Brand names: Follistim AQ Cartridge, Gonal-F, Gonal-f RFF
Drug class: Gonadotropins

Medically reviewed by Drugs.com on Feb 5, 2024. Written by Cerner Multum.

What is Gonal-F?

Gonal-F is used to treat infertility in women who cannot ovulate. Gonal-F is not effective in women with primary ovarian failure (when the ovaries are unable to produce an egg).

Gonal-F is also used in men to stimulate sperm production. This medicine is not effective in men with primary testicular failure (when the testicles are unable to produce sperm).

Gonal-F is often used together with another medication called human chorionic gonadotropin (hCG).

Gonal-F may also be used for purposes not listed in this medication guide.

Gonal-F side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Some women using this medicine develop ovarian hyperstimulation syndrome (OHSS), a potentially life-threatening condition. Stop using this medicine and call your doctor right away if you have symptoms of OHSS during or shortly after using Gonal-F:

Also call your doctor at once if you have:

Common side effects of Gonal-F may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not use Gonal-F if you have an untreated or uncontrolled endocrine disorder (thyroid, pituitary gland, or adrenal gland), heavy or abnormal vaginal bleeding that has not been checked by a doctor, an ovarian cyst, or cancer of the breast, ovary, uterus, testicle, hypothalamus, or pituitary gland.

Do not use this medicine if you are pregnant. You may need to have a negative pregnancy test before starting this treatment.

Before taking this medicine

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Gonal-F.

You should not use Gonal-F if you are allergic to it, or if you have:

Do not use this medicine if you are already pregnant. You may need to have a negative pregnancy test before starting this treatment. Tell your doctor right away if you become pregnant.

Tell your doctor if you have ever had:

Fertility treatment may increase your chance of having multiple births (twins, triplets, etc). These are high-risk pregnancies both for the mother and the babies. Talk to your doctor if you have concerns about this risk.

You should not breastfeed while using Gonal-F.

How should I use Gonal-F?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You must remain under the care of a doctor while using Gonal-F.

Gonal-F is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

You may need to mix Gonal-F with a liquid (diluent) before using it. When using injections by yourself, be sure you understand how to properly mix and store the medicine.

Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy or has particles in it. Call your pharmacist for new medicine.

To get pregnant, you may need to have sex daily for several days in a row. The timing of sex and medication dosing is important for Gonal-F to work.

You will need frequent medical tests.

If you use this medicine to get pregnant, you may also need occasional ultrasound exams. Based on your blood work, you may need to stop having sex for a short time. Follow your doctor's instructions very carefully.

Storing this medicine unopened (not in use):

Storing this medicine opened (in use):

Take the medicine out of the refrigerator and allow it to reach room temperature before injecting your dose. Do not heat the medicine.

Use a needle and syringe only once and then place them in a puncture-proof "sharps" container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Call your doctor for instructions if you miss a dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Gonal-F?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect Gonal-F?

Other drugs may affect Gonal-F, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.